Official websites use. Share sensitive information only on official, secure websites. Email: panduleni. Various preventive interventions have been implemented across the globe, but evidence for the effectiveness of these measures in reducing the incidence or prevalence of acute rheumatic fever and RHD is scattered.
This systematic review aims to assess the effectiveness of preventive interventions and identify the strategies used to reduce the burden of RHD. A comprehensive search was conducted to identify relevant studies on RHD prevention interventions including interventions for primordial, primary, and secondary prevention.
Effectiveness measures for the interventions were gathered when available. Narrative synthesis was performed, and the methodological quality appraisal was done using the Joanna Briggs Institute critical appraisal tools.
This systematic review underscores the importance of various preventive interventions in reducing the incidence and burden of Group A Streptococcus pharyngitis, acute rheumatic fever, and RHD. Rigorous evaluations and comprehensive analyses of interventions are necessary for guiding effective strategies and informing public health policies to prevent and reduce the burden of these diseases in diverse populations.
Keywords: acute rheumatic fever, RHD prevention, rheumatic heart disease, systematic review. Further research is essential to evaluate the actual effectiveness of current interventions in reducing the rheumatic heart disease burden. RHD is a significant public health problem and is among the leading causes of cardiovascular morbidity and mortality, with an estimated The inflammation is a result of acute rheumatic fever ARF , which is an autoimmune response to antigenic mimicry of a certain Group A Streptococcus GAS antigenic protein during a GAS bacterial infection of the pharynx.
