Official websites use. Share sensitive information only on official, secure websites. Even if some advantages are evident, difficulties that may arise for TMJ function after reconstruction originate from prosthesis contamination through oral mucosa dehiscence. The entire surgical planning and prosthetic fabrication were explained with specifications and the sequence of the surgical procedure. Finite elements analysis FEA was performed to check the force distribution and efficacy of the prosthetic device case 1 with hemi-mandibular resection and rehabilitation.
Although successful in these two cases, surgical reconstruction of the mandibular defect after resection by a CAD-CAM custom-made prosthesis still shows some drawbacks and failure risks. Several advantages of this technique and the surgical success in these two cases were presented, but limitations and side effects must be considered when cases are selected.
According to the World Health Organization definition, ameloblastoma is a benign intraosseous progressively growing epithelial odontogenic neoplasm characterized by expansion and a tendency for local recurrence if not adequately removed. It represents the second most common odontogenic tumor after odontomas, and it is mostly diagnosed in the fourth and fifth decades.
According to the clinical, histological, and radiographic characteristics, it could manifest as a uni-cystic, multi-cystic, peripheral, adenoid, and metastasizing form [ 1 , 2 , 3 ]. The treatment strategy for ameloblastoma consists of either resective or non-resective surgical therapy. It is possible, for surgical treatment, a conservative or a radical approach [ 4 ]. Conservative surgical treatments include enucleation with cauterization, curettage, cryotherapy, or marsupialization.
A radical surgical approach is a choice in the case of biologically aggressive subtypes of primary and recurrent ameloblastoma and it is based on en-bloc tumor resection with wide bone margin followed by immediate or delayed reconstruction of the surgical defect [ 5 ]. Non-surgical management of ameloblastoma consists of radiotherapy, chemotherapy, or target therapy and it is addressed to patients medically unstable for surgery or to treat ameloblastic carcinoma and recurrent ameloblastoma after multiple postsurgical recurrences [ 4 , 6 , 7 ].
