You have full access to this open access article. Diabetic nephropathy is a significant complication of diabetes and a leading cause of chronic kidney disease CKD globally. This study aimed to assess the decline of renal function and all-cause mortality and identify the contributing risk factors among Palestinian patients with diabetes.
The study employed a prospective cohort design, enrolling patients with type 2 diabetes mellitus T2DM attending primary health care centers in Palestine.
Subsequently, the patients were followed up for three years to assess renal function and identify significant associated risk factors. The primary outcomes examined were estimated glomerular filtration rate eGFR decline and all-cause mortality.
During the three-year follow-up, Hypertensive patients were 2. Regarding all-cause mortality, The risk of all-cause mortality was 5.
This study highlights the importance of early detection of CKD in patients with diabetes, prompting more comprehensive management of risk factors related to eGFR decline and mortality. Furthermore, it underscores the need for future research in this patient population, including investigations about other relevant risk factors and the impact of different medications, such as anti-diabetic and antihypertensive medications, on the GFR decline and mortality rate.
