Chronic bacterial prostatitis CBP is, usually, caused by uropathogens, especially gram-negative bacilli, although infection is sometimes due to Gram-positive and atypical microorganisms. A recent increasing in prevalence of Gram-positive strains has been reported. The aim of this study was to explore the epidemiological features and resistance rates in uropathogens isolated from CBP outpatients in last 10 years. All consecutive outpatients with demonstrated CBP attending a single Sexually Transmitted Disease centre from January and December , were enrolled and underwent microbiological cultures in first void early morning urine, midstream urine, expressed prostatic secretion, and post prostate massage urine.
Prevalence of different bacterial strains was stratified in four different periods: โ, โ, โ, โ Any changes observed in epidemiological features and resistance rates in uropathogens over the whole study period have been analyzed.
The present study has been planned, thus, as in vitro study. From 6, patients, 4, Gram-positive and 1, Gram-negative bacterial strains have been isolated. Enterococcus faecalis and Escherichia coli strains are the first and second frequent pathogens found, respectively.
Significant differences between E. Gram-positive organisms showed a decreasing of susceptibility to ciprofloxacin as well as Gram-negative strains, while a good susceptibility to the levofloxacin was evidenced. Moreover, a decreasing of activity of ciprofloxacin and a good activity profile of levofloxacin have been reported.
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