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If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. Loss of hemodynamic coherence is a phenomenon in critically ill patients.
Due to inflammatory events and endothelial remodeling, macro- and microhemodynamics are decoupled from each other, resulting in microcirculatory disturbances and end organ ischemia despite adequate vital parameters. Nailfold videocapillaroscopy NVC , however, is an established and easy method for visualization of the microcirculation in chronic diseases.
We here evaluated NVC in critically ill patients and compared its use with consensus microcirculatory assessment of IDF-microscopy. Evaluation of the CapMic score in 10 healthy volunteers at rest and under iatrogenic limb ischemia showed robust changes 0. Both sublingual and nailfold microcirculation deteriorated under rising norepinephrine- and crystalloid volume-requirements.
NVC-imaging provides comparable information on the microcirculation in critically ill patients compared to sublingual IDF microscopy.