
WEIGHT: 55 kg
Bust: 36
One HOUR:90$
NIGHT: +60$
Sex services: Extreme, Uniforms, BDSM, Pole Dancing, Ass licking
Official websites use. Share sensitive information only on official, secure websites. Conceived and designed the experiments: CG. Initiated and supported the project: GMi.
Discussed the results: GMo HM. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited. The trematode flatworms of the genus Schistosoma , the causative agents of schistosomiasis, are among the most prevalent parasites in humans, affecting more than million people worldwide.
In this study, we focused on two well-characterized strains of S. Both strains are highly inbred and exhibit differences in life history traits, in particular in their compatibility with the intermediate host Biomphalaria glabrata. We performed high throughput sequencing of DNA from pools of individuals of each strain using Illumina technology and identified single nucleotide polymorphisms SNP and copy number variations CNV. Based on a recently developed in-silico approach, we further detected 12 and 19 private i.
Functional annotation of transcripts lying in the private selective sweeps revealed specific selection for functions related to parasitic interaction e. Despite high differentiation between strains, we identified evolutionary convergence of genes related to proteolysis, known as a key virulence factor and a potential target of drug and vaccine development.
Our data show that pool-sequencing can be used for the detection of selective sweeps in parasite populations and enables one to identify biological functions under selection. Adaptation of parasites to their environment is governed by the principle of selection.